{"id":1644,"date":"2016-09-09T09:43:36","date_gmt":"2016-09-09T09:43:36","guid":{"rendered":"https:\/\/www.testofuel.com\/tf\/?p=1644"},"modified":"2017-02-09T11:50:22","modified_gmt":"2017-02-09T11:50:22","slug":"is-bulbine-natalensis-safe-the-side-effects","status":"publish","type":"post","link":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/","title":{"rendered":"Is Bulbine Natalensis Safe?: The Side Effects"},"content":{"rendered":"<p>With so many T-boosting supplements\u00a0on the market these days, you need to do your research to make sure you are getting something that will work, and more importantly that it is safe. The industry is rife with supplements that have unrealistic ingredients and unverified claims about their benefits.<\/p>\n<p>One supplement that is potentially unsafe is that of\u00a0<strong>Bulbine Natalensis<\/strong>. In this article we&#8217;ll look at the research as to why you should avoid it. Here&#8217;s what we&#8217;ll cover:<\/p>\n<ul>\n<li>What is Bulbine Natalensis?<\/li>\n<li>How does it work?<\/li>\n<li>Why is it unsafe?<\/li>\n<li>What safe alternatives are available?<\/li>\n<\/ul>\n<hr \/>\n<h2>What is\u00a0Bulbine Natalensis?<\/h2>\n<p>Bulbine Natalensis is a South African herb from the\u00a0<em>Asphodelaceae <\/em>family<em>. <\/em>Also known as<em>\u00a0<strong>Ibhucu, Rooiwortel <\/strong><\/em>and<strong><em> Ingcelwane,\u00a0<\/em><\/strong>It is an aloe-like, succulent plant characterized by rosette-shaped leaves and yellow spiked, star-shaped flowers.<\/p>\n<p>It is much touted for its medicinal properties, being used to treat mosquito bites, cracked skin, and to speed up wound healing.<\/p>\n<p>The plant is said to have\u00a0aphrodisiac qualities, as well as anti-diabetic and anti-convulsive properties too. All parts of the plant are used in some way or another and contain a range of bioactive compounds including <em><strong>alkaloids<\/strong><\/em>, <em><strong>saponins<\/strong> <\/em>and also\u00a0<em><strong>cardiac glycosides<\/strong><\/em> &#8211; compounds that\u00a0act on the contractile force of cardiac muscle.<\/p>\n<p>This supplement\u00a0is said to encourage an increase in strength, muscle size, fat loss and libido. It\u00a0has been seen to\u00a0elevate testosterone, at least in animal studies anyway.<\/p>\n<p>The proposed mechanism behind the supplement is that it increases <em><strong>g<\/strong><strong>onadotropin-releasing hormone (GnRH)\u00a0<\/strong>&#8211; <\/em>a master hormone that controls the production and release of your male hormones.<\/p>\n<p>A study published in <em>Pharmaceutical Biology <\/em>[1]<em>\u00a0<\/em>for example found that\u00a0dosing rats with\u00a025, 50 and 100 mg per kg of body weight significantly increased testosterone levels. Interestingly, the 50mg dosage increased T levels most &#8211; <strong>not only did the 100mg dose not increase T levels, it also elevated cholesterol.\u00a0<\/strong><\/p>\n<hr \/>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1672 size-full\" src=\"https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-Natalensis.jpg\" alt=\"bulbine-natalensis\" width=\"800\" height=\"451\" srcset=\"https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-Natalensis.jpg 800w, https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-Natalensis-150x85.jpg 150w, https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-Natalensis-300x169.jpg 300w, https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-Natalensis-768x433.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<hr \/>\n<h2>Is Bulbine Safe?<\/h2>\n<p>There is extremely limited human research to look at with regards to safety; and the research that is available will not fill you with confidence.<\/p>\n<p>To date there has only been one human study, and that only looked at short-term use of the supplement\u00a0[2]. The research was conducted as a &#8216;first step&#8217; into human trials to see if the supplement was safe in a clinical setting.<\/p>\n<p>In this trial, 36 men were given either a daily dose of 650mg of Bulbine or a placebo for 28 days. At the end of the study they were assessed for a number of different health panels including heart, liver and blood markers.<\/p>\n<p>Worryingly, <strong>the results suggested a\u00a0statistically significant increase in the liver enzyme, &#8216;a<\/strong><strong>lkaline phosphatase&#8217;<\/strong><em><strong>\u00a0<\/strong>&#8211; <\/em>an important enzyme produced in the liver that\u00a0helps break down proteins in the body. The study was also privately funded by a company that manufactures and profits from sales of this supplement which has its own potential issues.<\/p>\n<p>Similarly, rat studies have also shown that\u00a0oral ingestion alters liver enzymes and induces histological changes that are known to be adverse. One study [1] found that longer cycles\u00a0could have a negative impact on blood lipids, similar to\u00a0that of <strong><a href=\"https:\/\/www.testofuel.com\/tf\/how-do-anabolic-steroids-work\/\">androgenic anabolic steroids<\/a>.\u00a0<\/strong><\/p>\n<p>Lastly, the supplement was deemed\u00a0<strong>not completely safe <\/strong>by one group of researchers, after their study of rats found\u00a0selective toxicity in the liver and kidneys [3].<\/p>\n<hr \/>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1674 size-full\" src=\"https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Natalensis-Libido.jpg\" alt=\"natalensis-libido\" width=\"800\" height=\"450\" srcset=\"https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Natalensis-Libido.jpg 800w, https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Natalensis-Libido-150x84.jpg 150w, https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Natalensis-Libido-300x169.jpg 300w, https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Natalensis-Libido-768x432.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<hr \/>\n<h2>Summary &#8211; Should You Take Bulbine Natalensis?<\/h2>\n<p>Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. It has also been shown to exhibit potent aphrodisiac qualities.<\/p>\n<p>Animal studies show that it may increase testosterone, but only at specific doses &#8211; too high doses can have a negative impact on long-term health.<\/p>\n<p>Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time.<\/p>\n<p>We recommend that you opt for a much safer alternative with a proven track record of safety and results until more research has been conducted.<\/p>\n<hr \/>\n<h2>What Does Increase Testosterone Safely?<\/h2>\n<p>As a premium brand Anabolic Support Complex, <strong><a href=\"http:\/\/www.testofuel.com\/\">TestoFuel<\/a>\u00a0<\/strong>contains only the best best, natural ingredients scientifically proven to:<\/p>\n<ul>\n<li><strong>Muscle Growth and Strength\u00a0<\/strong>\u2013 Increase muscle\u00a0size and\u00a0create crazy strength<\/li>\n<li><strong>Improved Recovery\u00a0<\/strong>\u2013\u00a0Hit the gym more often<\/li>\n<li><strong>Enhanced Energy\u00a0<\/strong>\u2013 More motivation to train stronger for longer<\/li>\n<li><strong>Healthy Libido\u00a0<\/strong>\u2013 Ramp up sex drive and improve confidence<\/li>\n<\/ul>\n<p>TestoFuel is ideal for improving your performance\u00a0both in and out of the gym, and helping you attain that all-important muscular physique<\/p>\n<hr \/>\n<hr \/>\n<h2>References<\/h2>\n<ol>\n<li>Yakubu, MT et al.\u00a0<em>Anabolic and androgenic activities of Bulbine natalensis stem in male Wistar rats.\u00a0<\/em>Pharm Biol. 2010; 48(5): 568-76<\/li>\n<li>Hofheins, JE et al.\u00a0<em>Short term safety of bulbine natalensis supplementation in healthy men.\u00a0<\/em><span class=\"JournalTitle\">Journal of the International Society of Sports Nutrition.\u00a0<\/span><span class=\"ArticleCitation_Year\">2012;\u00a0<\/span><span class=\"ArticleCitation_Volume\">9(Suppl 1): 33<\/span><\/li>\n<li>Afolayan, AJ et al.\u00a0<em>Effect of Bulbine natalensis Baker stem extract on the functional indices and histology of the liver and kidney of male Wistar rats.\u00a0<\/em>J Med Food. 2009; 12(4): 814-20<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>With so many T-boosting supplements\u00a0on the market these days, you need to do your research to make sure you are getting something that will work, and more importantly that it is safe. The industry is rife with supplements that have unrealistic ingredients and unverified claims about their benefits. One supplement that is potentially unsafe is [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":1673,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[255,253,254],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.2.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Is Bulbine Natalensis Safe?: The Side Effects - TestoFuel Blog<\/title>\n<meta name=\"description\" content=\"Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. It has also been shown to exhibit potent aphrodisiac qualities. Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. We recommend that you opt for a much safer alternative with a proven track record of safety and results until more research has been conducted.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Is Bulbine Natalensis Safe?: The Side Effects - TestoFuel Blog\" \/>\n<meta property=\"og:description\" content=\"Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. It has also been shown to exhibit potent aphrodisiac qualities. Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. We recommend that you opt for a much safer alternative with a proven track record of safety and results until more research has been conducted.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/\" \/>\n<meta property=\"og:site_name\" content=\"TestoFuel Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/TestoFuel\/\" \/>\n<meta property=\"article:published_time\" content=\"2016-09-09T09:43:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-02-09T11:50:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-T-Booster.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"451\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lee\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@testofuel\" \/>\n<meta name=\"twitter:site\" content=\"@testofuel\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lee\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/\",\"url\":\"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/\",\"name\":\"Is Bulbine Natalensis Safe?: The Side Effects - TestoFuel Blog\",\"isPartOf\":{\"@id\":\"https:\/\/www.testofuel.com\/tf\/#website\"},\"datePublished\":\"2016-09-09T09:43:36+00:00\",\"dateModified\":\"2017-02-09T11:50:22+00:00\",\"author\":{\"@id\":\"https:\/\/www.testofuel.com\/tf\/#\/schema\/person\/265972121a38bf60ea404977c4f0a738\"},\"description\":\"Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. It has also been shown to exhibit potent aphrodisiac qualities. Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. 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It has also been shown to exhibit potent aphrodisiac qualities. Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. We recommend that you opt for a much safer alternative with a proven track record of safety and results until more research has been conducted.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/","og_locale":"en_US","og_type":"article","og_title":"Is Bulbine Natalensis Safe?: The Side Effects - TestoFuel Blog","og_description":"Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. It has also been shown to exhibit potent aphrodisiac qualities. Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. We recommend that you opt for a much safer alternative with a proven track record of safety and results until more research has been conducted.","og_url":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/","og_site_name":"TestoFuel Blog","article_publisher":"https:\/\/www.facebook.com\/TestoFuel\/","article_published_time":"2016-09-09T09:43:36+00:00","article_modified_time":"2017-02-09T11:50:22+00:00","og_image":[{"width":800,"height":451,"url":"https:\/\/www.testofuel.com\/tf\/wp-content\/uploads\/2016\/09\/Bulbine-T-Booster.jpg","type":"image\/jpeg"}],"author":"Lee","twitter_card":"summary_large_image","twitter_creator":"@testofuel","twitter_site":"@testofuel","twitter_misc":{"Written by":"Lee","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/","url":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/","name":"Is Bulbine Natalensis Safe?: The Side Effects - TestoFuel Blog","isPartOf":{"@id":"https:\/\/www.testofuel.com\/tf\/#website"},"datePublished":"2016-09-09T09:43:36+00:00","dateModified":"2017-02-09T11:50:22+00:00","author":{"@id":"https:\/\/www.testofuel.com\/tf\/#\/schema\/person\/265972121a38bf60ea404977c4f0a738"},"description":"Bulbine Natalensis is a South African shrub that has been used in traditional medicine to treat a variety of conditions including diabetes and convulsions. It has also been shown to exhibit potent aphrodisiac qualities. Animal studies show that it may increase testosterone, but only at specific doses - too high doses can have a negative impact on long-term health. Ultimately, this product is relatively new. The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. We recommend that you opt for a much safer alternative with a proven track record of safety and results until more research has been conducted.","breadcrumb":{"@id":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.testofuel.com\/tf\/is-bulbine-natalensis-safe-the-side-effects\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.testofuel.com\/tf\/"},{"@type":"ListItem","position":2,"name":"Is Bulbine Natalensis Safe?: The Side Effects"}]},{"@type":"WebSite","@id":"https:\/\/www.testofuel.com\/tf\/#website","url":"https:\/\/www.testofuel.com\/tf\/","name":"TestoFuel Blog","description":"Natural Testosterone Booster","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.testofuel.com\/tf\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.testofuel.com\/tf\/#\/schema\/person\/265972121a38bf60ea404977c4f0a738","name":"Lee","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.testofuel.com\/tf\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/5019bcd84afdcab74210ea9ae881dbcc?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/5019bcd84afdcab74210ea9ae881dbcc?s=96&d=mm&r=g","caption":"Lee"},"url":"https:\/\/www.testofuel.com\/tf\/author\/leemuscle16\/"}]}},"_links":{"self":[{"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/posts\/1644"}],"collection":[{"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/comments?post=1644"}],"version-history":[{"count":5,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/posts\/1644\/revisions"}],"predecessor-version":[{"id":1676,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/posts\/1644\/revisions\/1676"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/media\/1673"}],"wp:attachment":[{"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/media?parent=1644"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/categories?post=1644"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.testofuel.com\/tf\/wp-json\/wp\/v2\/tags?post=1644"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}